Penns Creek is a census-designated place in Snyder County, Pennsylvania. Penns Creek is located at 40°51′38″N 77°3′30″W / 40.86056°N 77.05833°W, bordered on the north by its namesake creek, Penns Creek. It lies along PA Route 104 between Middleburg to the south and Mifflinburg to the north.
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