was systemically administered to mice with AAV neutralizing antibodies, the gene transfer efficiency in the brain and liver decreased to 5–15%. However, by loading AAV9 into the nanomachine ...

Of particular concern is the virus’s liking for the liver. “If you look at ... administered them to mice intravenously, and compared delivery efficiencies of the GFP molecules across the brain.

UCLA Health researchers have discovered significant changes in liver function following exposure to diesel exhaust in a controlled study involving mice.

A gene therapy to correct a mutation that causes maple syrup urine disease prevented newborn death and normalized growth in a calf as well as in mice.

Mice rendered infertile through ovary cell–targeting mutations ... “I tried all the available viruses,” Shinohara says, including multiple variations of adeno-associated viruses (AAV), which are ...

This vector was administered into the cerebral ventricular spaces of Scn1b-null mice. Following treatment, the AAV-Navβ1 vector successfully expressed the β1 subunit protein in both excitatory ...