Complex V, the central enzyme in energy conversion, dissipates the proton gradient across the membrane, catalyzing the phosphorylation of ADP to ATP. In normally functioning mitochondria, ...

It has been shown that inhibition of GTPase-activating protein of ADP-ribosylation factor (Arf), ArfGAP, with a small molecule (QS11) results in synergistic activation of Wnt/β-catenin signaling.

image: Molecular dynamic simulation of ADP and acetyl phosphate view more . Credit: Aaron Halpern, UCL ... /Life sciences/Cell biology/Cellular physiology/Cellular processes/ Phosphorylation ...

ATP, adenosine triphosphate, is used by all cells as an energy intermediate. During cellular respiration, energy is captured when a phosphate is added to ADP (adenosine diphosphate) to generate ...