Glyoxalase Domain-containing Protein 4 (GLOD4), the First Identified in a New Class of Enzymes Called Nitrases, Generates Nitrated ...

A team that includes a RIKEN researcher has refined a lab test for measuring protein aggregate levels in samples from ...

A phase 2 trial of Lundbeck’s alpha-synuclein-targeting drug Lu AF82422 has failed to reach statistical significance in patients with multiple system atrophy (MSA), although the company says the ...

A fluorescent micrograph of a section of brain affected by Parkinson's disease. Neuron nuclei are blue, while the protein ...

This article originally appeared in Research Colorado.Research at the University of Denver is showing promise for the ...

Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's ...

BioArctic AB (publ) (Nasdaq Stockholm: BIOA B) announced today that the US FDA Office of Orphan Products Development (OOPD) has granted orphan drug designation (ODD) to exidavnemab for the treatment ...

Lewy body dementia (LBD) and Parkinson’s disease dementia share a common cause: abnormal deposits of a protein called alpha-synuclein that form in the brain. These deposits, known as Lewy bodies ...

Annovis Bio Inc. (NYSE: ANVS) ("Annovis"), a late-stage clinical drug platform company pioneering transformative therapies ...

The findings reveal that TFE3 activation facilitates the clearance of toxic alpha-synuclein aggregates and restores mitochondrial function, two crucial aspects of PD progression. As a leading ...

The discovery, published on Friday in the journal Science, centers on a protein called FAM171A2, which the researchers found plays a crucial role in the spread of pathological alpha-synuclein ...