fumigatus has important implications for the scope of clinical antifungal stewardship. Given the human health consequences of disease caused by azole-resistant Aspergillus, it is hardly surprising ...

An example of this is an antifungal drug class called the azoles. There is strong evidence to suggest that azole resistance .

Scientists have discovered that the most widely-used class of antifungals in the world causes ... weapons against fungal plant diseases are azole fungicides. These chemical products account ...

fumigatus, azole-resistance represents a clinically ... the same problem may affect other antifungals with novel mechanisms of action that are in development. For example, the medical antifungal ...

The findings, reported in Nature Communications, also solve a decades-long scientific puzzle that’s prevented drugmakers from successfully using azole antifungal drugs to treat visceral ...

Second, there is a greater chance of drug interactions. Azole antifungals (e.g., fluconazole, itraconazole and voriconazole) alter metabolism of cyclophosphamide, a cytotoxic agent, through ...

EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi: Amsterdam, The Netherlands Monday, February 3, 2025, 17:00 Hrs [IST] For the first time, t ...