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Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.
A new set of genes that contribute to Parkinson’s disease risk has been identified.
One big challenge is the tumor’s structure. It has a dense microenvironment ... powerful gene-editing tool—straight into tumor cells. CRISPR is like a pair of molecular scissors that can ...
Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human immune cells.
Using CRISPR-based engineering methods to ... The team found that 80% of the stem cells organize themselves into a structure that mimics the most basic form of an embryo after a few days, and ...
In future experiments, the scientists aim to learn more about how CRISPR systems protect bacteria cells from viruses that don't go dormant, Modell says. "We know CRISPR systems are one of the ...