CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

In particular, CRISPR is being used to develop chimeric antigen receptor (CAR) T-cell therapies where immune cells are genetically engineered to attack specific tumors. In addition, some companies ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more ...

The second tool is the CRISPR-Cas9 system, which allows easy and precise editing of any region of the genome. When it comes to traditional immortalized cell lines, such as HeLa or HEK293, cutting with ...