The core components of CRISPR-based genome-editing therapies are bacterial proteins called nucleases that can stimulate unwanted immune responses in people, increasing the chances of side effects ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Researchers at the (Belgium) have uncovered a previously unknown mechanism that regulates the immune response against parasites.

Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning. We get into more ...

Stanford researchers introduced affordable gene-editing kits ready for the classroom, aiming to make the field more accessible for high school students.

In response to infection, immune cells stream into tissues to fight ... "We are expanding our CRISPR pooled spatial screening to profile the impacts of many types of genetic perturbations at ...

However, despite huge success with high early response rates ... providing an important step forward in the use of CRISPR in immune cell therapies” A recent report indicates that autologous ...

ZUG, Switzerland and BOSTON, Jan. 13, 2025 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious ...

CRISPR Therapeutics ... and enhance cell fitness. This immune-evasive cell replacement therapy is designed to enable patients to produce their own insulin in response to glucose.