The research shows that novel cancer drugs designed to inhibit CDK7 can, within minutes, shut down gene expression pathways that drive cell proliferation in dozens of different kinds of tissues.

Human and chimpanzee neural progenitor cells and cortical organoids were analyzed to assess enhancer activity and cell proliferation.. Genome editing was employed to generate mouse models ...

The proliferation of progenitor cells in response to injury is a crucial step in the regeneration of sensory receptors, but this process is blocked in the mammalian inner ear and retina.