Bile duct inflammation and scarring, known as cholangiopathies, can disrupt bile flow, leading to liver damage and ...

Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary ...

A needle biopsy of the liver on the eleventh postoperative day showed, in addition to cholestasis, marked, diffuse fatty degeneration, which probably antedated the operation and was related to the ...

Treatment of this autoimmune liver disease should also address various symptoms and complications arising from any associated autoimmune diseases, particularly cholestasis and cirrhosis-related ...

Cholestasis is a condition in which the flow ... but its role in cholestatic liver injury remains unclear. Here the authors show that targeting ACER3, a ceramidase upregulated in cholestatic ...

Predictive Safety Testing Consortium have proposed glutamate dehydrogenase (GLDH) as a more liver-specific biomarker for ...

The prevalence of depressive-like behavior is significantly higher in patients with cholestatic liver disease ... underlying the association between cholestasis and clinical depression.

is one of the most common causes of neonatal cholestasis and accounts for over half of children who undergo liver transplantation. In biliary atresia, a number of prenatal or perinatal insults to ...

Autoimmune liver diseases (ALDs), including autoimmune ... leading to chronic intrahepatic cholestasis. Characterized by ...

Protara Therapeutics (TARA) announced that data from THRIVE-1, a prospective, observational study evaluating the prevalence of choline ...