Drug-induced liver injury including cholestasis is another form of acquired liver disease, accounting for approximately 2 to 5% of hospitalizations for jaundice, 10% of cases of hepatitis in all ...

However, often the onset of hepatic injury by drugs may be delayed from days to several months. Liver biopsy is not performed in every single instance of drug-induced cholestasis. However ...

The changes in liver morphology described in this patient are almost identical to those reported in the 5 biopsies from the other patients with the syndrome of recurrent intrahepatic cholestasis.

Chronic cholestasis can lead to liver fibrosis and cirrhosis ... viral infections, drug-induced injury, and alcohol-related damage, whereas extrahepatic cholestasis often results from bile ...