The rest of this HIV-1 envelope protein, which is docked on a gray membrane, are the structures of gp120 and gp41, shown in green, and the transmembrane segment, shown in blue. Disclaimer ...

Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir ...

in gp120/gp41 that lead to exposure of the gp41 ectodomain; Extension of the gp41 fusion peptide causes a membrane fusion reaction between the viral membrane and the target cell membrane through ...

Interestingly, both antibodies recognize a cryptic epitope on the native HIV-1 envelope trimer but do not bind gp120 or gp41 in enzyme-linked immunosorbent assays. The discovery of broadly ...

Recently, these researchers have determined the three-dimensional structure of the HIV-1 Envelope trimeric ectodomain (“Env”), comprised of three gp120 and three gp41 subunits, in its ...

Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must bind with the CD4 receptor on the membrane of ...