Medically reviewed by Steffini Stalos, DO CD4 T helper cells are a type of white blood cell called a lymphocyte that serves ...

T-cell activation involves two phases, enabling a more precise immune response. This insight may boost cancer immunotherapy ...

CD4 + conventional T (Tconv) cells, or helper T cells, inspect the peptides presented by dendritic cells. If the peptides are foreign antigens, the T cells expand in numbers and transform into an ...

Advancements in mRNA vaccine technology are reshaping medicine, addressing challenges and expanding applications from ...

A team from the Max Planck Research Group for Systems Immunology at the University of Würzburg has identified a previously unknown phase of the immune response. The results, published in Science, ...

Researchers have identified a previously unknown phase of the immune response. These new insights have significant implications for the development of vaccines and cellular immunotherapies.

Tolerogenic dendritic cells in the intestines are shown to reduce the immune responses caused by exposure to food proteins.

This occurs in specific lymph node areas that are accessed thanks to CXCR3 expression on CD8 T cells. There, they receive IL-2 from CD4 helper T-cells. Without this signal, CD8 T-cells cannot ...

the T cells are supposed to lay off. During an autoimmune response, the helper T cells don't distinguish between foreign peptide antigens and self-peptides properly and go on the attack no matter ...