Medically reviewed by Steffini Stalos, DO CD4 T helper cells are a type of white blood cell called a lymphocyte that serves ...

T-cell activation involves two phases, enabling a more precise immune response. This insight may boost cancer immunotherapy ...

Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.

CD4 + conventional T (Tconv) cells, or helper T cells, inspect the peptides presented by dendritic cells. If the peptides are foreign antigens, the T cells expand in numbers and transform into an ...

USC researchers have developed an innovative type of cancer-fighting immune cell, the EchoBack CAR T-cell, that uses focused ...

Advancements in mRNA vaccine technology are reshaping medicine, addressing challenges and expanding applications from ...

Researchers have identified a previously unknown phase of the immune response. These new insights have significant implications for the development of vaccines and cellular immunotherapies.

This occurs in specific lymph node areas that are accessed thanks to CXCR3 expression on CD8 T cells. There, they receive IL-2 from CD4 helper T-cells. Without this signal, CD8 T-cells cannot ...

Tolerogenic dendritic cells in the intestines are shown to reduce the immune responses caused by exposure to food proteins.

The team tested the impact on eight novel helper plasmids with different deletions in the E2 and E4 genes on four rAAV serotypes. They discovered that some deletions affected productivity, reducing ...

the T cells are supposed to lay off. During an autoimmune response, the helper T cells don't distinguish between foreign peptide antigens and self-peptides properly and go on the attack no matter ...