Hereditary hemochromatosis is an inherited iron ... They need to be in a range where optimal hepcidin levels and iron absorption intersect. Some of the guidelines recommend a target SF level ...

In people with hemochromatosis, however, iron absorption is dramatically increased. This is due to a genetic deficiency of hepcidin, a hormone produced in the liver that regulates iron absorption.

Although the majority of genetic iron-overload syndromes have now probably been identified, several paths of investigation remain open. First, clinical experience strongly indicates that some iron ...

Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin deficiency ... patients with hemochromatosis, an iron overload disorder ...

I was diagnosed with Hemochromatosis in 1979. But my story pales in comparison to the many folks I have met on the Net who have been diagnosed with iron overloading from genetic Hemochromatosis.

Plasma, available in a subset of patients, had been collected in the presence of EDTA and stored at −70°C and was therefore unsuitable for measurement of iron levels. The soluble transferrin ...