T-cell activation involves two phases, enabling a more precise immune response. This insight may boost cancer immunotherapy ...

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance.

Previous work by the team had shown that the NOTCH signaling pathway played a central role in differentiation, which is essential for an effective immune response by CD8 + T cells. In the new ...

Brain tissue analysis of an animal model has revealed the potential role of immune system dysfunction in the onset and ...

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance.

The immune system is comprised of various cells that work in concert to fight off disease. The two immune responses, innate and adaptive, are orchestrated to build a specific reaction to the invading ...

Immune checkpoint inhibitors, a class of immunotherapies that help immune cells attack cancer more effectively, have revolutionized cancer treatment. However, fewer than 20% of patients respond to ...

This study uncovers dynamic immune adaptations during pregnancy through single-cell RNA sequencing of peripheral blood ...