Contrary to prior belief, certain T-cells remain in lymph nodes for a long time and store information about immune reactions there. That’s been discovered by researchers at the University of Würzburg ...

In contrast, T-cell clonal expansion was clearly observed in pancreatic lymph nodes of diabetic subjects 1 and 2 (Table 3 and Supplementary Tables 1 and 2), where over half of the T-cell clones ...

Primary T-cell responses in lymph nodes (LNs) require contact-dependent information exchange between T cells and dendritic cells (DCs). Because lymphocytes continually enter and leave normal LNs ...

Regulatory T cells (Tregs) in the lymph nodes play a key role here, suppressing excessive or misdirected immune responses there. The immune system is fast when it comes to fighting viruses, ...

Stem-like T cells in lymph nodes serve to replace exhausted T cells in the tumor microenvironment (TME), exposing a new development opportunity for immunotherapies. A recent study from the Yale Cancer ...

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells. But new findings from a clinical trial by researchers at UC San Francisco and ...

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing ...

Activation of immune cells in the lymph nodes leads to the production and release of antibodies, and activation of lymphocytes, including T cells, to battle infection.

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

Some B cells that reside in the lymph nodes acquire molecules from the surface of pathogens, and they present these so-called antigens to T cells. The T cells will then be activated if they have a ...

Nodes (N): If the cancer's spread to nearby lymph nodes, and if so, how many. Metastasis (M): If cancer cells have traveled to other parts of your body. Based on that data, your doctor can then ...