Patterning of the nephron along the proximal–distal ... and the developmental defects found in human patients. Induction of the kidney occurs through reciprocal interactions between an ...

These important genetic associations identified in human renal hypoplasia have ... in the MM leading to a 50% decrease in both kidney size and nephron number in adult mice (33).

Each kidney contains over one million microscopic filtering units called nephrons. Each nephron is made of a tubule and is responsible for 'cleaning' the blood by removing urea and excess water ...

Using a mouse model of AKI, the research team first demonstrated the therapeutic potential of human iPS cell-derived nephron progenitor cells (hiPSC-NPCs). When these cells were transplanted into the ...

More information: Long term expandable mouse and human induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease, Cell Stem Cell (2024). DOI ...

The 12th workshop will be held from May 12 - 16, 2025 focusing on hands-on whole kidney and single nephron function analysis and models of acute and chronic kidney disease. Please contact Dr. Volker ...

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