Hemophilia, a rare inherited bleeding disorder, is primarily caused by mutations in specific genes that impair the body’s ...

Point mutations are often thought of as the raw material of evolution; these small changes include the substitution of one nucleotide with another (often referred to as a single-nucleotide ...

The mutations that were successfully silenced are ... Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision, Science ...

The method first takes a given SARS-CoV-2 spike protein sequence and simulates all possible single-point mutations. For each mutated version of the protein, DNMS uses the ProtBERT model to ...

RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in ...