Hemodialysis (HD)-related factors also alter drug clearance. Vigabatrin: in patients with renal impairment the dose should be decreased based on creatinine clearance. The effect of dialysis on ...

The trial size adjustment, along with protocol modifications and the addition of higher-enrollment sites, is expected to ...

Although few Asian countries have renal replacement therapy (RRT) registries, the number of patients with end-stage renal disease (ESRD) is clearly growing in this region. ...it is estimated that ...

Vigabatrin is indicated as monotherapy for children with infantile spasms and as adjunct therapy for adults ... eliminated primarily by renal excretion as an unchanged drug and has an elimination ...