and that the centrosomes nucleate the growth of the spindle microtubules. During mitosis, many of the spindle fibers attach to chromosomes at their kinetochores (Figure 6), which are specialized ...

Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

Same as in mitosis, except that the spindle fibers from each centriole attach to one chromosome of a matching chromosome pair. In other words, the fibers from one centriole attach to 23 ...

A hallmark of tumor cells is an inability to control their proliferation, which implies that these cells are capable of bypassing cell cycle checkpoints and regulation by tumor suppressor signaling ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Mitotic spindles are dynamic, self-organizing, intracellular structures that are essential for cell division. Spindles are composed of proteins, cytoskeletal elements and microtubules, which are a key ...

E.R. Steuer, L. Wordeman, T.A. Schroer, M.P. Sheetz, "Localization of cytoplasmic dynein to mitotic spindles and kinetochores," Nature, 345:266-68, 1990. Michael ...

Focusing on the centromere—the part of each chromosome that interacts with spindle microtubules to direct segregation in mitosis or meiosis—we found that the structure’s size determines the direction ...

It can be seen in the stages shown above that mitosis maintains the chromosome number or complement of a cell. Mitosis therefore maintains the chromosome complement and ensures that each daughter ...

A large structure called the mitotic spindle also forms from long proteins called microtubules on each side, or pole, of the cell. During prometaphase, the nuclear envelope that encloses the ...

The spindle fibers from both of the centrioles attach to each one of the chromosomes. Same as in mitosis, except that the spindle fibers from each centriole attach to one chromosome of a matching ...