The network meta-analysis revealed a 49% reduction in all-cause mortality and a 39% reduction in major adverse cardiovascular events when compared to high-dose statin therapy alone.

What scant data there is on use of ezetimibe in children with severe hypercholesterolemia suggests "reasonable" LDL-lowering ...

Previous experimental studies have indicated that statins, widely prescribed for cholesterol reduction, possess properties such as anti-inflammatory, antifibrotic, and antioxidant effects.

Any risk for hemorrhagic stroke associated with statins needs to be balanced with the 26% relative reduction in ischemic stroke per mmol/L reduction in LDL-C that these drugs afford.

Combining statins with another drug, ezetimibe, significantly reduces the risk of death in patients with clogged arteries, according to findings published Sunday in Mayo Clinic Proceedings.

WASHINGTON — Statin use was associated with up to a 90% risk reduction for new-onset primary sclerosing cholangitis among patients with inflammatory bowel disease, according to data presented at ...

At 12 weeks, AZD0780 30mg taken once-daily led to a 50.7% reduction in LDL-C. Similar efficacy was observed regardless of whether trial participants received moderate- or high- intensity statin ...

The 2012 CTT meta-analysis was acknowledged in the 2013 Cochrane Review, which noted statin therapy "demonstrated a consistent 20% relative risk reduction in major vascular events with statins ...

Also, reduction in the risk of stroke due to statin prescription showed a dose-response relationship on the risk of cardiovascular disease due to air pollutant exposure.

Bempedoic acid demonstrated effectiveness in reducing the risk of cardiac events along with statins. Study authors reported that this medication could potentially act as an alternative to more ...

At 12 weeks, AZD0780 30mg taken once-daily led to a 50.7% reduction in LDL-C. Similar efficacy was observed regardless of whether trial participants received moderate- or high- intensity statin ...