Background. A 17-year-old white male with Crohn's disease who was receiving maintenance infusions of the anti-tumor necrosis factor (TNF) agent, infliximab, presented with a new-onset psoriasiform ...

Terbinafine, an allylamine antifungal, inhibits biosynthesis of ergosterol, an essential component of fungal cell membrane, via inhibition of squalene epoxidase enzyme. This results in fungal cell ...

The case highlights that this cutaneous complication is the result of a drug class effect and that it can occur in children, as well as adults, with IBD. The development of psoriasiform skin ...

A 17-year-old white male with a 9-year history of ileocolonic Crohn's disease developed a skin rash while receiving infliximab, a chimeric IgG1κ monoclonal antibody against tumor necrosis factor ...