The anticonvulsant topiramate causes dose-dependent weight loss in humans and in animal models of diabetes. Toplak and colleagues, therefore, investigated the efficacy and safety of topiramate as ...

Topiramate, an antiepileptic drug with potential mechanisms of action including sodium channel blockade, inhibition of glutamate receptors, and enhancement of γ-aminobutyric acid (GABA ...

This study aimed to evaluate the long-term efficacy and safety of topiramate in treating children with drug-resistant epilepsy. A multicentric, retrospective, open-label, add-on study was ...