Tumor invasion and angiogenesis are reduced ... in combination with angiostatin (inhibitor of endothelial cell proliferation) in a dual-action clinical treatment.

The tumor has now invaded the tissue beyond the basement membrane. Individual cells from the tumor enter into the network of newly formed blood vessels, using these vessels as highways by which ...

Inhibition of EZH2 disrupts key signaling pathways that drive tumor proliferation, invasion, and survival. Beyond its canonical role in H3K27 trimethylation, EZH2 has been found to regulate non ...

Nerves are important routes of tumor spread in H&N malignancies, yet the biology and prognostic implications of perineural tumor growth are not fully understood. On balance, the available evidence ...

tumor invasion and neo-angiogenesis. Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the ...

Ophthalmology Times - ophthalmology news, articles, and events in a timely and accurate manner for members of the ophthalmic ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Proliferation index is an important prognostic factor in breast cancer. The Ki-67 protein is expressed in all phases of the cell cycle except G0 and serves as a good marker for proliferation. Studies ...

Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the nasopharyngeal epithelium. Due to its concealed location and nonspecific ...