The basic structural and functional unit of the kidney is the nephron, which performs a multitude of tasks including blood filtration, re-absorption of salt, water and other compounds required by ...

Each kidney contains over one million microscopic filtering units called nephrons. Each nephron is made of a tubule and is responsible for 'cleaning' the blood by removing urea and excess water ...

In a study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system ...

Genetic studies performed in humans and mutant mice have implicated a number of critical genes, in utero environmental factors and molecular mechanisms that regulate nephron endowment and kidney size.

More information: Toshikazu Araoka et al, Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models, Science Translational Medicine (2025). DOI: ...

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