" A good rule of thumb is to cook brisket for about 1 to 1.5 hours per pound at 225 degrees Fahrenheit, " Piva told Chowhound. But, he cautioned, don't just rely on the clock.

For a 5-pound brisket in roughly 3 cups of liquid with some vegetables surrounding it, it takes about 4 hours. Focus on the temperature and not the time it will take to cook, Goldwyn emphasizes.

In a slow cooker, add the brisket, enough water to cover it, and the spices from the spice packet or your own spices. Cook on low for 9 to 11 hours or high for about 4½ hours.

Because of this, Christopher Prieto recommends treating chuck like brisket in terms of your cooking timeline. That means a long, slow cook — typically around 12 to 18 hours, depending on the ...

That's because brisket needs to be cooked above 160 degrees for an extended period of time to melt the connective tissue and collagen, making it tender, but the long cook makes it easy to go ...