News

Scientists have imaged the toxic clumps and fibres made by expanded huntingtin with cutting-edge microscopes, helping us to understand the exact way they can be assembled and how their structure could ...
In Huntington’s disease research, biomarkers are the secret weapon for spotting treatment effects. A new blood study uncovers two proteins, CAP1 and CAPZB, that, with additional work, could help track ...
The gut and brain are connected by a busy two-way superhighway. In Huntington’s disease, traffic on this road may be jammed, detoured, or carrying harmful cargo, linking gut microbes, inflammation, ...
Some childhood experiences stay with us, quietly shaping how we feel as adults. For those raised in families with Huntington’s disease, this new study helps make sense of those feelings, and reminds ...
Casgevy is the first CRISPR-based drug to make its way through the approval process, all but curing Sickle Cell Disease and it’s paving the way for similar drugs targeting other diseases. Is ...
The HDBuzz editorial team had a virtual sit-down with HDBuzz founder, editor emeritus, Huntington’s disease (HD) researcher, and neurologist Professor Ed Wild. We laughed, we cried… actually we just ...
Researchers have detected early changes in brain scans and biomarkers in young people with the Huntington’s disease gene, 20 years before symptoms are predicted to appear. These findings could help ...
The Huntington Study Group (HSG) is a clinical research network focused on accelerating treatments for Huntington’s disease (HD). This year, the annual conference is being held in Cincinnati, where ...
People who develop Huntington’s disease (HD) are born with the genetic change that causes the disease. So why does it take decades, usually around 40 to 50 years, for the symptoms of the disease to ...
Researchers have updated the system that classifies Huntington’s disease progression. Tracking progression in 4 stages will make clinical trial screening and data interpretation easier and faster, and ...
Huntington’s disease disrupts genetic "traffic lights," keeping genes green when they should be red. These genetic traffic jams may act to speed brain cell aging and faulty traffic cops fail to stop ...
As we wave goodbye to 2024, the HDBuzz team reflects on a year marked by significant progress, challenges, and hope. From breakthroughs at the lab bench, advancements in drug development, and both ...