Tirzapetide dose escalation schedules were slower in the real-world than clinical settings among individuals with obesity without T2D.

They were randomized to either titration of that dose up to 4.5 mg or switched to tirzepatide titrated up to 15 mg (or maximum tolerated doses of both). Most in both groups were also taking oral ...

Medication doses were gradually increased to 15 mg for tirzepatide or 4.5 mg for dulaglutide, or to the highest maximum dose a participant could tolerate. The study’s primary and secondary ...