The autophagy-lysosomal pathway is activated via ... including Taxol resistant A549 Taxol cells. This study revealed that Hdy-7 induces ROS-mediated lysosomal biogenesis and retards cell growth ...

SEATTLE — A community meeting was held at Seattle’s Denny Blaine Park Sunday afternoon, just days after a group of neighbors near the popular park filed a lawsuit against the city demanding it ...

In a historic two-day rout last week, the world’s 500 wealthiest individuals have collectively lost more than half a trillion dollars, marking the steepest loss ever recorded on the Bloomberg ...

Some supplements and drinks may break a fast. This can depend on whether they contain certain ingredients, including sugar. Fasting is becoming a popular lifestyle choice. Fasts don’t last ...

When you fast, the cells in your body start a cellular waste removal process called autophagy. In this process, the cells break down and metabolize broken and dysfunctional proteins that build up ...

These PARP14/ADPr condensates contain key components of p62 bodies—including the selective autophagy receptor p62, its binding partner NBR1 and the associated protein TAX1BP1, along with K48-linked ...

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, ...

Autophagy is a cellular degradation process that plays a crucial role in maintaining metabolic homeostasis under conditions of stress or nutrient deprivation. This process involves sequestering, ...

School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, College Green, Dublin 2 D02 PN40, Ireland Trinity Translational Medicine Institute, Trinity College ...

Mammalian target of rapamycin (mTOR) is pivotal for cell growth and metabolism. The downstream targets of mTOR regulate protein translation and cell autophagy to affect orthoflavivirus replication, ...