When you fast, the cells in your body start a cellular waste removal process called autophagy. In this process, the cells break down and metabolize broken and dysfunctional proteins that build up ...

2023). PCD comprises ferroptosis, apoptosis, autophagy, pyroptosis, and the recently uncovered cuproptosis. In summary, the molecular mechanism involved in ferroptosis is closely related to ...

These PARP14/ADPr condensates contain key components of p62 bodies—including the selective autophagy receptor p62, its binding partner NBR1 and the associated protein TAX1BP1, along with K48-linked ...

In a historic two-day rout last week, the world’s 500 wealthiest individuals have collectively lost more than half a trillion dollars, marking the steepest loss ever recorded on the Bloomberg ...

The autophagy-lysosomal pathway is activated via ... including Taxol resistant A549 Taxol cells. This study revealed that Hdy-7 induces ROS-mediated lysosomal biogenesis and retards cell growth ...

School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, College Green, Dublin 2 D02 PN40, Ireland Trinity Translational Medicine Institute, Trinity College ...

Autophagy is a cellular degradation process that plays a crucial role in maintaining metabolic homeostasis under conditions of stress or nutrient deprivation. This process involves sequestering, ...

Sunitinib is an approved therapy for treatment of patients with PNETs, but low response rates and resistance have limited its impact, with autophagy and sunitinib sequestration in the lysosome ...

Enduring a week’s worth of cold water plunges can jolt the body’s cells into starting the process of autophagy to clean up and recycle old, worn-out, and broken parts, according to a new study.

I am Reader and Principal Investigator at the University of Surrey, United Kingdom. I obtained my PhD in Virology in the University of Barcelona. I then joined the laboratory of Claude Krummenacher ...