Eledon Pharmaceuticals (ELDN) announced that tegoprubart, the company’s investigational anti-CD40L antibody, was used as a key component of the ...

Genesis, a biotechnology company developing human-compatible engineered organs to address the global organ shortage, today announced the successful transplantation of a genetically engineered porcine ...

We demonstrate here that administration of a CD154-specific monoclonal antibody (hu5C8) allows for renal allotransplantation in outbred, MHC-mismatched rhesus monkeys without acute rejection.

We were thereby able to demonstrate for the first time that renal allotransplantation is accompanied by an increased frequency of Innate E(+) CD8 T-cells together with an exacerbated senescent ...

These first cases were performed in patients outside the regular criteria for allotransplantation (transplantation between human beings), which could compromise the success of these transplants.

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Cell reprogramming concepts have been classically developed in the fields of developmental and stem cell biology and are currently being explored for regenerative medicine, given its potential to ...

Autoimmune disorders occur when immune cells go wrong and attack the body’s own tissues. Currently, autoimmune disorders are largely treated by broad immunosuppressive agents and blocking antibodies, ...