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This pivot away from one-size-fits-all vaccine recommendations underscores the urgent need for next-generation immunization strategies - precisely the role that GeoVax's multi-antigen COVID-19 ...
Using T cell receptor sequencing on both functionally expanded T cells and neoantigen-loaded tetramer-sorted T cells, we identified tumor antigen-specific T cell receptors,” write the investigators.
In June 2024, the government granted GeoVax $24.3 million to run a 10,000-participant phase 2b study for its next-gen COVID vaccine.
Genomic determinants of antigen expression hierarchy in African trypanosomes. Nature, 2025; DOI: 10.1038/s41586-025-08720-w ...
An influenza virus with surface glycoprotein spikes hemagglutinin (HA, trimer, red) and neuraminidase (NA, tetramer, purple). [ KATERYNA KON/SCIENCE PHOTO LIBRARY/1386012927/Science Photo Library ...
Neoself-antigens are the primary target for autoreactive T cells in human lupus. Cell, 2024; DOI: 10.1016/j.cell.2024.08.025 ...
Given that autoantibodies to neoself-antigens are frequently found in patients with autoimmune diseases, the researchers explored T cell reactivity in patients with lupus and in mice, in which Ii ...
By comparison, rapid antigen tests for older kids, teens, and adults will more often miss an RSV infection due to lower viral loads. Healthy older kids and adults usually don’t need a test for RSV.
In the article that accompanies this editorial, Kwak et al 6 demonstrate using individual patient data from randomized trials that patients who achieve a low prostate specific antigen (PSA) nadir 6 ...
Among more than 11,000 participants, 1.7% had at least one false positive rapid antigen test on the basis of RT-PCR results. Persistent false positives tended to occur in women and in persons with ...
What is a hepatitis B surface antigen and why do doctors test for it? Read on to learn more about this blood test, including why doctors test for it and how to interpret test results.
Antigen Detection Raw Materials An antigen is a molecule (such as protein) that causes the immune system to produce antibodies and trigger an immune response. In the case of COVID-19, structural ...
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