The 8-year data may hold value for TAVI—the newest Sapien valve uses the same tissue—but many other variables differ.

"The decision between a bioprosthetic and a mechanical valve is one of the most consequential for patients requiring aortic ...

Increasing numbers of patients require aortic valve surgery ... either a homograft or the pretreated stentless xenograft bioprosthesis. Survival of patients after 8 years was about 80% for ...

aHR 1.12 favoring bioprosthetic valves (95% CI 0.97-1.29) These findings were consistent in sensitivity analyses excluding pure aortic insufficiency, intermediate- or high-risk patients ...

CALC is the principal failure mode of BHV fabricated from glutaraldehyde pretreated porcine aortic valves or bovine pericardium. Covalent binding of APD to residual glutaraldehyde in pericardial ...