Scientists have discovered that the most widely-used class of antifungals in the world causes ... weapons against fungal plant diseases are azole fungicides. These chemical products account ...

fumigatus, azole-resistance represents a clinically ... the same problem may affect other antifungals with novel mechanisms of action that are in development. For example, the medical antifungal ...

Since mid-2002, two new antifungal drugs — voriconazole, a third-generation azole, and caspofungin ... efficacy (because of their specific mechanisms of action), more favourable toxicity ...

Fluconazole, a very safe and effective azole antifungal, requires a much higher dose in children (12 mg/kg/day) compared with adult patients. In addition, the neonatal field is exploring ...