Mechanisms of antifungal drug resistance involve alterations in the sequence ... For instance, in C. albicans, azole resistance was associated with the presence of an isochromosome (5L) which resulted ...

33 The results of the present study indicate that TTO and terpinen-4-ol have antifungal activity against Candida strains. The mechanism of action of TTO ... alternifolia Cheel (tea tree) oil against ...

EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi: Amsterdam, The Netherlands Monday, February 3, 2025, 17:00 Hrs [IST] For the first time, t ...

fumigatus has important implications for the scope of clinical antifungal stewardship. Given the human health consequences of disease caused by azole-resistant Aspergillus, it is hardly surprising ...

Second, there is a greater chance of drug interactions. Azole antifungals (e.g., fluconazole, itraconazole and voriconazole) alter metabolism of cyclophosphamide, a cytotoxic agent, through ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...

Human fungal pathogens exemplify a severe threat to health due to their complex infection strategies and the host's immune system's failure to eradicate ...