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Both myelinating and non-myelinating Schwann cells are covered by a basal lamina. The outside of the lamina is surrounded by a layer of connective tissue namely the endoneurium, which contains ...
The capillary basal lamina (BL) located between the endothelial cell, pericyte and perivascular astrocyte plays important roles in normal and diseased central nervous system (CNS). Using ...
Hemidesmosomes (light blue) connect intermediate filaments of a cell to the basal lamina, a combination of extracellular molecules on other cell surfaces. Gap junctions ...
In these so-called dystroglycanopathies, too few sugar groups are added to alpha dystroglycan, leading to a version of the protein that does not attach properly to the basal lamina. Detachment of ...
Immunostaining also showed a thinning of the basal lamina in 5 of these patients. Further analyses showed punctate hypointensities linked to congested blood vessels in 10 patients.
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