eLife3d
Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...
BMJ5d
Targeting the IL-6–Yap–Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis
Objective We aimed to understand the role of the transcriptional co-factor Yes-associated protein (Yap) in the molecular pathway underpinning the pathogenic transformation of synovial fibroblasts (SF) ...
eLife3d
Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
Biomedical Research Institute, Shenzhen Peking University-the Hong Kong University of Science and Technology Medical Center, Shenzhen, China Division of Life Science, the Hong Kong University of ...