This case suggests that using stem cells with the CCR5-delta-32 mutation may not be necessary to achieve long-term HIV remission. If so, this would make it easier to find suitable donors for ...

The bone marrow he received came from a donor whose genes carried a rare mutation that made them resistant to HIV, known as CCR5-delta 32, which was transferred on to Brown. Traces of the virus ...

The anonymous patient is the first to achieve long-term HIV remission — in this case approaching 6 years — after receiving a single CCR5 delta 32 mutation. Specifically, the patient received a ...

The concern is due to evidence that individuals with the delta 32 deletion in the CCR5 gene (which leads to little or no expression of the CCR5 receptor on the cell surface) have a higher prevalence ...

Their findings pinpoint the emergence of the CCR5 delta 32 mutation, which disables a key protein that HIV uses to infect immune cells. This mutation became increasingly common between 8,000 and ...

Researchers used so-called "zinc finger nuclease (ZFN) technology" -- what they referred to as "molecular scissors" -- to modify T cells in the immune system to mimic the CCR5-delta-32 mutation ...

The Berlin patient had received a transplant from a healthy CCR5 delta 32 variant. The reason for his cure and much excitement since.