CRISPR: From Discovery To Clinic—And Charting A Path Forward
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
Impacts4d
Unveiling the Power of CRISPR Screening in Modern Genomics
CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...
The Scientist4mon
Cell Engineering 101: Editing with CRISPR
Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.
The Motley Fool1y
The Best CRISPR Companies to Invest In
In particular, CRISPR is being used to develop chimeric antigen receptor (CAR) T-cell therapies where immune cells are genetically engineered to attack specific tumors. In addition, some companies ...
The EMBO Journal3d
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
Phys.org15d
Complex engineering of human cell lines reveals genome's unexpected resilience to structural changes
Structural variation is a change in the structure of an organism's genome ... In a new study, the team used a combination of ...
The Scientist12mon
Using CRISPR to Edit Genes in Induced Pluripotent Stem Cells
The second tool is the CRISPR-Cas9 system, which allows easy and precise editing of any region of the genome. When it comes to traditional immortalized cell lines, such as HeLa or HEK293, cutting with ...