Current CRISPR guide RNAs are designed based on European reference genomes, leading to false-negative results in cells from ...

Rare genetic diseases are challenging for patients and their families—made all the more overwhelming because symptoms tend to ...

Our goal is to expand the application of CAR-T cell therapies and improve their effectiveness so that solid tumors can also be effectively treated with CAR-T cells.

A Ph.D. graduate student in biomolecular engineering at UC Santa Cruz, with a background in computer science and mathematics, ...

A glucose-sensitive nanovaccine delivers CRISPR to tumors, silences immune-suppressing genes, and activates a targeted immune ...

Using a new CRISPR-based methodology for modulating DNA structure to enact epigenetic control over specific genes, a team of researchers has identified a “master regulator” gene capable of improving T ...

Parse Biosciences announced today the launch of CRISPR Detect, enabling single cell pooled CRISPR screens at unprecedented scale.

A groundbreaking clinical trial is testing CAR T cells created using CRISPR gene-editing technology.

The United Kingdom has become the first country to give regulatory approval to a medical treatment involving the revolutionary CRISPR gene editing tool.

FDA approves first CRISPR therapy—here’s how it works against sickle cell The landmark treatment turns on another blood protein that prevents sickling.

Sickle cell disease, long ignored by drugmakers, turned out to be a perfect target for the flashy gene editing tool CRISPR. The question is, what next?

My research lab specializes in determining the structure and function of newly discovered and obscure CRISPR systems. Due to its gene editing potential, CRISPR has caught the imagination of the ...