In particular, CRISPR is being used to develop chimeric antigen receptor (CAR) T-cell therapies where immune cells are genetically engineered to attack specific tumors. In addition, some companies ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

A new set of genes that contribute to Parkinson’s disease risk has been identified.

Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human immune cells.

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

Using CRISPR-based engineering methods to ... The team found that 80% of the stem cells organize themselves into a structure that mimics the most basic form of an embryo after a few days, and ...

In future experiments, the scientists aim to learn more about how CRISPR systems protect bacteria cells from viruses that don't go dormant, Modell says. "We know CRISPR systems are one of the ...