The primary focus Patient-Derived Xenograft (PDX) Core is to develop ... are now available from validated PDX models provided by the PDX core. Please see the Advanced Cell Engineering and 3D Models ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing their ability to infiltrate solid tumours.

Supported [in part] by a Medical Research Future Fund Stem Cell Therapies Mission grant (APP2016039), National Health and Medical Research Council of Australia grant (APP2008300, APP2017898, ...

Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach. iScience. 2022 Dec 12;26(1):105799. PMID: 36619972; PMCID: PMC9813793.