Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...

AUTX-703, a novel and potent oral KAT2A and KAT2B protein degrader, inhibits growth and induces profound, persistent cell state differentiation in SCLC modelsNEWTON, Mass., April 03, 2025 (GLOBE ...

Expression data from patient-derived xenograft (PDX) mouse models exposed to micvotabart pelidotin (MICVO) indicate gene signatures associated ...

Novel trispecific T cell engager, ZW209, demonstrates potent preclinical efficacy against DLL3-expressing tumors and an encouraging safety ...

Cancer Cell Swirling inside every cell are millions of microscopic ... This type of experiment, called a patient-derived xenograft, is considered a gold standard for showing a drug’s potential to beat ...

Researchers explore how natural compounds in traditional Chinese medicine can modulate cholesterol metabolism to combat ...

In fact, one recent study reported that TCM-derived compounds like quercetin ... by inhibiting the growth of clear cell renal carcinoma (ccRC) xenograft tumors in a dose-dependent manner.