A global study reveals that cutting-edge cancer immunotherapies, while lifesaving, carry a hidden risk: they may trigger cholestasis, a serious liver condition where bile flow stalls.

Higher peak bile acid levels and maternal BMI are independent risk factors associated with worsening pruritus in women with intrahepatic cholestasis of pregnancy.

Researchers discovered immune checkpoint inhibitors (ICIs)—revolutionary cancer drugs—significantly increase the risk of cholestasis, a rare bile buildup that damages the liver. Younger patients (<65) ...

A global study reveals that cutting-edge cancer immunotherapies, while lifesaving, carry a hidden risk: they may trigger cholestasis, a serious liver ...

Cholestasis is a buildup of bile, something our bodies make to help digest food, in the blood. Many different conditions can lead to cholestasis including pregnancy.

Intrahepatic cholestasis or pregnancy (ICP also known as obstetric cholestasis) is usually seen as itching during later stages of pregnancy. In mild cases it is not harmful but severe cases may ...

17. Schaffner, F., and Popper, H. Morphologic studies of cholestasis. Gastroenterology 37:565–573, 1959. Crossref PubMed Web of Science Google Scholar ...

Sometimes, a friend's Facebook comment can save a life. After Christina DePino complained in a Facebook post about itching during her pregnancy, friends cautioned that she may have cholestasis ...

Is Neonatal Cholestasis a Marker of Future Liver Damage? —This study examined the natural history of infants born with alpha-1 antitrypsin (AAT) deficiency and liver disease, with a focus on ...

Cholestasis research is still an emerging field, but Dr. Mays has been examining it for decades after his hospital had three stillbirths over the course of two years in the early 2000s.

On Dr. Berlin's Informed Pregnancy Podcast, Kate Mara recalls being diagnosed with Cholestasis and eventually having to undergo an emergency c-section Kate Mara‘s birth plan didn’t exactly ...

EstebanMezey, M.D., Gilbert R.Cherrick, M.D., and Peter R.Holt, M.D. Author Info & Affiliations Published August 1, 1968 N Engl J Med 1968;279: 241 - 248 DOI: 10.1056/NEJM196808012790504 VOL ...