This work is published in Nature in the article, “ Clonal tracing with somatic epimutations reveals dynamics of blood ageing. ” In youth, humans have between 50,000 to 200,000 active blood ...

Clonal hematopoiesis did not occur significantly more often among patients who received hematopoietic stem cell transplantation than their donors, according to findings of a correlative laboratory ...

The immune system effectively modulates self-reactive B cells through negative selection mechanisms, including clonal deletion, clonal anergy, and receptor editing, which suppress their proliferation ...

Siphonophores are unusual animals made up of individual organisms called "zooids," which each have a distinct function — despite being genetically identical.

Researchers pinpoint a cellular process called 'clonal hematopoiesis' as a new risk factor for cardiovascular problems. In the future, this may lead to targeted, personalized treatments.

To the known risk factors for cardiovascular disease - high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity - a new one has to be added: clonal ...

Researchers identified 17 new genes positively selected for clonal hematopoiesis in a large U.K. Biobank cohort, revealing their impact on aging and disease risks.

Researchers at the RUDN Laboratory of Biology of Single Cells have studied the possibilities of DNA sequencing at the level of individual cells in patients with a rare form of childhood leukemia ...

Amgen subsidiary deCODE Genetics has identified new risk factors and genes associated with clonal hematopoiesis, a precursor state to blood cancer. | The company reported that whole-genome ...

Recent larger-scale studies of patients with cancer and longitudinal population cohorts have revealed how age-related expansions of mutant hematopoietic cells (clonal hematopoiesis [CH]) have ...

Study illuminates precancerous 'clonal outgrowth' in blood cells Date: September 22, 2022 Source: Weill Cornell Medicine Summary: A common, spontaneous mutation in blood stem cells, which has been ...

Researchers sought to determine whether there was an association between the presence of clonal hematopoiesis of indeterminate potential and protection from Alzheimer’s disease.