A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Biohacking has moved from niche experiments to a global movement reshaping how we think about human potential. With ...

The innovation, he says, could transform the way scientists measure and address genomic breaks in gene-editing systems.

Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease ...

such as incorporation of uracil into DNA or base mismatches, can be mutagenic and toxic to replicating cells. To discover factors in repair of genomic uracil, we performed a CRISPR knockout screen in ...

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA. It can also modify gene ...

Racial disparities in mortality are increasing. This article explores how the production of DNA-edited ethnically diverse ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Cell culture is a key technique in scientific research. It lets scientists grow and study cells outside their natural ...

The gene-edited GMOs to be exempted are those classed as the products of SDN1 (gene disruption) and SDN2 (gene modification). As with the recent deregulation of gene-edited GMOs in England, the New ...