As skin-care ingredients go, adapalene (like the popular over-the-counter option Differin) and its prescription cousin tretinoin have a lot in common. Both are retinoids—vitamin A derivatives ...

With hundreds of skincare products and new ingredients stocking store shelves, it's tough to know what's going to actually ...

adapalene is among the best-tolerated topical retinoids—especially compared to stronger options like tretinoin or tazarotene. What a reviewer says: “My dermatologist recommended Differin to ...

While prescription tretinoin can be effective, it is often more expensive, and costs can depend on your insurance plan. Adapalene is more accessible because it’s available over the counter. You can ...

All products featured on Vogue are independently selected by our editors. However, we may receive compensation from retailers and/or from purchases of products through these links. Love retinol ...

What to look for: Most studies on OTC niacinamide used formulas with 2 to 5 percent concentrations, and research shows that ...

Consistency is key when using retinol, because it could take several weeks before you start seeing noticeable results.

Save $5 off any purchase of $25 on select Cetaphil and Differin products.Amazon Differin is probably the best-known OTC adapalene-based product. The brand says it’s a good all-over face ...

Adapalene was once available only with a prescription but is now sold OTC (it's the active ingredient in Differin). Because of that, Romanowski says it has some of the best evidence of being ...

When it comes to skincare, good things take time. We’re all guilty of impatiently waiting to see the benefits of adding a step to our nightly skincare routines, no matter if it’s using a new ...

Promising review: "You might think you're exfoliating your skin but TRUST ME, you haven't been. You'll be SHOCKED and maybe even a little disgusted when you see how much skin comes off on these ...