Department of Chemistry, Center for Diagnostics and Therapeutics, Advanced Translational Imaging Facility, Georgia State University, Atlanta, Georgia 30303, United States ...

medma.uni-heidelberg.de Liver fibrosis is characterised by the excessive deposition of extracellular matrix (ECM) in response to chronic and sustained liver damage, triggering a prolonged wound ...

causing the lethal hepatic fibrosis seen in Ecm1-KO mice. MMPs mediate LTGF-β1 activation by proteolytic cleavage of LAP.27 To investigate whether ECM1 affects the proteolytic activity of MMP-2 or MMP ...

In the early stages of the COVID-19 epidemic, it was widely considered that young, otherwise healthy people were at low risk ...

vMember of the German Center for Lung Research and Cardiopulmonary Institute, and Agaplesion Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany Study group members are listed in appendix.

Anyone, of any ethnicity, can get cystic fibrosis. But for decades it has been overlooked in people of color, leading to misdiagnoses and dismal health disparities. Terry Wright takes a pulmonary ...

Patients with clinically distinct ILDs, whether CTD-related or not, can exhibit a pattern of common clinical disease behaviour (declining lung function, worsening respiratory symptoms and higher ...

Currently, available treatments to block liver fibrosis are designed to eliminate the underlying causes of liver disease. The lack of truly effective drugs to regress or reverse fibrosis is a major ...

bDepartment of Pediatrics, University of Washington, Seattle, WA, USA cDepartment of Biostatistics, University of Washington, Seattle, WA, USA dTranslational Medicine Research Institute, The Hospital ...

Pre-clinical and interim clinical results underscore GRI-0621’s potential to have both anti-inflammatory and anti-fibrotic effects in pulmonary fibrosis Results from 6-week interim analysis (n=24) in ...