royalbluemersey.sbnation14d
Everton 4-0 Leicester: Final | Dominant performance from Moyes’ boys
Fulltime Thoughts - Everton started off hot and didn’t let off, thumping Leicester City to add to their cushion over the relegation zone below them. A 4-0 win, all goals from open-play and no new ...
Sports Illustrated25d
Ohio State’s Dominant Performance Over Notre Dame Summed Up in Two Wild Stats
Notre Dame's Riley Leonard engineered one of the most impressive drives of the college football season to start Monday's national championship game. Since that opening salvo from from the Fighting ...
eLife25d
Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
The authors analyze a variety of PIK3R1 mutants (i.e. deltaExon11, E489K, R649W, and Y657X), which reveals a range of phenotypes that support the proposed model for dominant negative activity. The use ...
eLife25d
Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
Figure 3. SHORT syndrome p85α mutations impair phosphotyrosine-stimulated phosphoinositide 3-kinase activity. Lipid kinase activity of purified recombinant PI3K complexes generated using baculoviral ...
Medical Xpress1mon
Study explores link between people's professions and their genetic predisposition to neuropsychiatric traits
Polygenic scores (PGS) are metrics used to estimate the genetic predisposition of people to developing specific mental health conditions, personality traits or diseases. In recent years ...