The mammalian brain is known to produce mental representations of the spatial environment, known as cognitive maps, that help ...

How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...

A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse. Researchers have ...

A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse.

This study investigates the role of Aff3ir-ORF2, a novel nested gene variant, in disturbed flow-induced endothelial cell activation and atherosclerosis. We demonstrate that disturbed shear stress ...

Endothelial stiffening induced by Western diet was proposed ... We further propose that fatty acids may activate RhoA by inducing its dissociation from Rho-GDI1.

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Researchers explore the role of a high-fat diet in promoting the formation of premetastatic niches and platelet activation.

The research team, headed by Professor Pla-Martín from the Institute of Biochemistry and Molecular Biology I at HHU, has identified a specialized recycling system, which cells activate when they ...

Among these, benign non-immune cells, including cancer-associated fibroblasts (CAFs), adipocytes, endothelial cells (ECs), pericytes (PCs), Schwann cells (SCs) and others, are crucial factors for ...