Stalevo® is a combination of levodopa, carbidopa and entacapone. It was initially approved based on pharmacokinetic studies demonstrating bioequivalence with Sinemet® immediate release (IR ...

A new study has revealed that the widely prescribed Parkinson's disease drug entacapone significantly disrupts the human gut microbiome by inducing iron deficiency. The findings, published in ...

Expert Rev Neurother. 2009;9(7):929-940. Improvements in levodopa pharmacokinetics with the addition of entacapone were similar to that seen in healthy volunteers. In addition, Phase II trials ...