"By showing that entacapone induces iron deficiency, we have uncovered a new mechanism of drug-induced gut dysbiosis, in which the drug selects for E. coli and other potentially pathogenic ...

The Parkinson’s disease drug entacapone disrupts gut microbiome homoeostasis via iron sequestration. Nature Microbiology, 2024; DOI: 10.1038/s41564-024-01853-0 ...

Introduction to Disease State Parkinson's disease (PD) is a chronic, progressive neurological disorder characterized pathologically by the loss of dopamine neurons in the pars compacta of the ...

Author for correspondence Departments of Neurology, Molecular Pharmacology and Physiology, Parkinson's Disease and Movement Disorders Center, University of South Florida, 5 Tampa General Circle ...